A (14;22) Robertsonian translocation, 45 chromosomes
نویسندگان
چکیده
منابع مشابه
A rare non-Robertsonian translocation involving chromosomes 15 and 21.
CONTEXT Robertsonian translocations (RT) are among the most common balanced structural rearrangements in humans and comprise complete chromatin fusion of the long arm of two acrocentric chromosomes. Nevertheless, non-Robertsonian translocation involving these chromosomes is a rare event. CASE REPORT We report a de novo unbalanced translocation involving chromosomes 15 and 21. The newborn was ...
متن کاملPericentromeric organization at the fusion point of mouse Robertsonian translocation chromosomes.
In mammals, Robertsonian (Rb) translocation (the joining of two telo/acrocentric chromosomes at their centromere to form a metacentric) is the most effective process in chromosomal evolution leading to speciation; its occurrence also affects human health (through the induction of trisomies) and the fertility of farm animals. To understand the mechanism of Rb translocation, we used the house mou...
متن کاملrobertsonian translocation between chromosomes (no.21/14) in relation to the history of spontaneous abortion in a family
background: approximately 205 million pregnancies occur each year in the worldwide. on the other hand, spontaneous abortion has been reported in 15-20% of all diagnosed pregnancies. the most common cause of spontaneous abortion is chromosomal abnormalities of the embryo. robertsonian translocation carriers specially 21-14 are the most common balanced rearrangement among the carrier couples with...
متن کاملRobertsonian translocation between chromosomes (no.21/14) in relation to the history of spontaneous abortion in a family
BACKGROUND Approximately 205 million pregnancies occur each year in the worldwide. On the other hand, Spontaneous abortion has been reported in 15-20% of all diagnosed pregnancies. The most common cause of spontaneous abortion is chromosomal abnormalities of the embryo. Robertsonian translocation carriers specially 21-14 are the most common balanced rearrangement among the carrier couples with ...
متن کاملCd branding studies in a homologous Robertsonian 13;13 translocation.
A phenotypically normal female with a history of two miscarriages was found to have the karyotype 45,XX,t(13p:13p). C banding showed the translocation to have two regions of centromeric constitutive heterochromatin, silver staining showed an active NOR in 60% of the cells screened, and Cd banding studies showed a single Cd band with absence of the Cd band at the suppressed centromere.
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ژورنال
عنوان ژورنال: Cytogenetic and Genome Research
سال: 1973
ISSN: 1424-859X,1424-8581
DOI: 10.1159/000130476